Looking at the Trecento through the lens of current global paradigms and concerns in historical and art historical studies might seem hazardous, or even paradoxical and provocative at best. Very few other labels have the power to evoke both the glories, achievements and limitations of traditional ‘Western’, and namely Eurocentric, art history. As a matter of fact, using the Italian word Trecento to mean the ‘Fourteenth Century’ in the visual arts, music and potentially any area of human endeavour adumbrates a clear hierarchy–with Italy at its top. It is meaningful, and perhaps no coincidence, that the term Trecento came into use in English in the same years that mark the tumultuous expansion of the new discipline of art history in the late nineteenth and early twentieth centuries and its usage has grown exponentially ever since. While much has been done in recent decades to broaden our understanding of the period both geographically and philosophically, the Trecento remains primarily the century of Giotto and of the great Tuscan painters and sculptors. At this time of building national ‘walls’, it seems particularly appropriate to think that the seminal and transformative character of the Trecento owes much to artistic and cultural exchanges, movement of artists and patrons, circulation of models and ideas across Italy, Europe, the Mediterranean and beyond. Our aim is to bring into conversation recent research on these issues.